Tie Me Up, Tie Me Down: Inhibiting RNA Polymerase
نویسندگان
چکیده
منابع مشابه
Tie Me Up, Tie Me Down: Inhibiting RNA Polymerase
Mechanistic understanding of antibiotic action can yield crucial insights that aid in the design of new antibiotics. In this issue, Mukhopadhyay et al. (2008) uncover the mechanism by which the antibiotic myxopyronin inhibits bacterial RNA polymerase, suggesting a new target region in RNA polymerase for inhibitor design.
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ژورنال
عنوان ژورنال: Cell
سال: 2008
ISSN: 0092-8674
DOI: 10.1016/j.cell.2008.09.052